Selection of In Vivo Relevant Dissolution Test Parameters for the Development of Cannabidiol Formulations with Enhanced Oral Bioavailability
Background: Cannabidiol (CBD) shows interesting therapeutic properties but has yet to demonstrate its full potential in clinical trials partly due to its low solubility in physiologic media.Two different formulations of CBD (amorphous and lipid-based) Pouch have been optimized and enable an increase in bioavailability in piglets.In vivo studies are